Dissemination of Tubercle Bacilli.

DIFFERENTIATION OF LEPROSY AND TUBERCLE BACILLI. 219 On the Differentiation of Leprosy and Tubercle Bacilli

On the nucleoproteins of avian tubercle bacilli.

The nucleic acids of tubercle bacilli have formed the subject of several studies, among which may be mentioned those by Ruppel (l), Levene (2), and Johnson and his associates (3-5). The work of Mensel and Heidelberger (6) on the fractionation of the proteins of the tubercle bacillus revealed the presence of several protein fractions, rich in phosphorus and in purines, which appeared to be nucle...

The Effect of Spermine on Tubercle Bacilli

A crystalline substance capable of suppressing the growth of a variety of mycobacteria in vitro has been isolated from extracts of tissue in acidified dilute ethanol. This inhibitory material was found to be equally active against virulent, attenuated, and avirulent variants of human and bovine tubercle bacilli, but had little or no effect on saprophytic mycobacteria and on several non-acid-fas...

The Colony Morphology of Tubercle Bacilli

The colony topography of tubercle bacilli is significantly affected by altering the pH of the culture medium on which the organisms are grown. Under the conditions of these experiments, avian tubercle bacilli produce two variants, rough and smooth. The former are most numerous on the most acid medium used (pH 6.0); the smooth colonies are obtained over a broad range of pH. Three colonial varian...

Simplified Fluorescence Microscopy of Tubercle Bacilli

The fluorescence of tubercle bacilli stained with auramine and rhodamine does not require ultra-violet light. It can be caused by blue light up to 406mp. A’copper sdphate ammonia liquid filter, suitably diluted, will transmit this waveband. A gelatin screen filter, absorbing all light below 510mp. is used in the eyepiece. Normal, high intensity projection Alament lamps, combined with lamp conde...